Excessive testing in emergent evaluation of children with first unprovoked seizure

نویسندگان

  • Fariba Khodapanahandeh Pediatric Department of Rasool-e- Akram Hospital, Sattar Khan AvenueNiyaesh Street, Tehran, Iran,
  • Homayoon Hadizadeh Radiology Department of Rasool-e-Akram Hospital, Iran University of Medical Sciences.
  • Mona Nematian Rasool-e-Akram Hospital, Iran University of Medical Sciences.
چکیده مقاله:

  Abstract   Backround: The first episode of an afebrile seizure is a common cause of admission   of children to emergency departments. Alot of tests are routinely performed for these patients. The cost of such an evaluation is high and benefits are doubtful. We conducted   this study in order to evaluate the results of the tests and find out what tests are necessary for children with first unprovoked seizure.   Methods: In a 7-year retrospective study files of 150 children aged between 1 month   and 14 years admitted with first afebrile seizure to the pediatric ward of Rasool Akram   hospital were reviewed. Reports of the brain neuroimaging studies (Ct-scan & MRI) and   laboratory tests were extracted.   Results: 150 patients with a mean age of 53 ± 48 months qualified for inclusion in the   study. 143 (95%) of 150 children with first afebrile seizure were imaged. Ninety percent   (128/143) had normal neuroimaging. Emergent computed tomography as the initial   study was performed in 90% (128/143) and MRI in 10% (15/143 ). Sixty patients had   both MRI and CT-scans. Clinically significant neuroimaging abnormalities were reported   in only 9.7% (14/143). There was a significant relation (P<0.001) between focal   seizures and abnormal neuroimaging. Children under 24 months of age were also more   prone to have abnormal imaging (p<0.002). Laboratory tests including complete blood   count (CBC) and chemistry panel (Na, K, Ca, BUN, Cr) were performed for all. Only   two patients had low serum calcium level, later diagnosed as vitamin D resistant rickets.   Conclusions: The most important aspect of management of a child after a first   afebrile seizure is careful history taking and physical examination. Laboratory tests   should be requested in very limited situations. Emergent brain CT-scans are recommended for children with focal seizures, abnormal findings on physical examination, presence of any predisposing factors and those under 24 months of age.  

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عنوان ژورنال

دوره 22  شماره 1

صفحات  17- 21

تاریخ انتشار 2008-05

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